The MACRO Trial
The aim of the second workstream in the MACRO Programme is to run a large randomised controlled trial (RCT) to produce evidence about the effectiveness and role of medical treatment (long-term antibiotics) and sinus surgery in adults with Chronic Rhinosinusitis (CRS) both with and without polyps.
The MACRO trial aims to recruit 600 patients from 17 sites in the UK and will begin recruiting patients in Autumn 2018.
If you are a patient suffering from CRS and would like to know more about the MACRO Trial, please visit the Information for Participants page. If you are interesting in participating in the MACRO Trial, please contact you GP or ENT specialist. A list of our participating hospitals can be found on the Recruiting Centres page
If you are a researcher and would like more information regarding the trial, please visit the Information for Researchers page or contact the MACRO Trial Team. The protocol and accompanying trial documents will be available to download from this website shortly.
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Trial opened to recruitment: December 2018 |
The MACRO Trial is jointly led by Professor Claire Hopkins and Professor Carl Philpott, along with a multi-disciplininary team of researchers form University College London (ULC), University of Southampton and the Oxford Surgical Intervention Trials Unit (SITU).
If you would like to contact the clinical trial office, please email the MACRO Clinical Trial Manager, Stephen Jones
The MACRO Trial is funded by the NIHR Programme Grants for Applied Research (ref RP-PG-0614-20011).
The MACRO Programme is sponsored by University College London (UCL).
What is a clinical trial
For more information on what a clinical trial is and why it's so important to undertake them, please visit the NHS Choices website
Information for Participants
For further information regarding the MACRO Trial, please visit the Information for Participants page.
Information for Researchers
For further information regarding the MACRO Trial, please visit the Information for Researchers page.
Recruiting Centres
To see which hospitals will be recruiting patients for the MACRO trial visit the Recruiting Centres page.
