Skip to main content
Home
  • THE MACRO TRIAL
    • Information for Participants
      • Interested in Participating in the MACRO Trial
      • Already a MACRO participant
    • Recruiting Sites
  • NEWS
User account menu
  • Log in

The MACRO Programme Home

  • Copyright SITU 2017
    MACRO logo
    The MACRO Trial

The MACRO Trial


The MACRO Trial has now closed to recruitment.

The MACRO Trial is a randomised controlled trial (RCT) to produce evidence about the effectiveness and role of medical treatment (long-term antibiotics) and sinus surgery in adults with Chronic Rhinosinusitis (CRS) both with and without polyps.

The MACRO trial aims to recruit 600 patients from at least 17 sites in the UK and began recruiting patients in Autumn 2018.

If you are a patient suffering from CRS and would like to know more about the MACRO Trial, please visit the Information for Participants page. If you are interested in participating in the MACRO Trial, please contact you GP or ENT specialist. A list of our participating hospitals can be found on the Recruiting Centres page.

Deatils of participating in the trial are provided in our Patient Information Sheet

The MACRO Trial is part of the MACRO Programme, which is made up of experts in sinus disease and breathing disorders, GPs, research experts and patient representatives. The programme is running in three sections of research over 7 years to establish the best treatment pathway for adults with CRS and ensure that this pathway is put into practice by GPs and hospital doctors. This should then make lives better for CRS patients and at the same time reduce ineffective use of healthcare resources within the NHS.

If you would like more information regarding the trial, please contact the trial team on macrotrial@nds.ox.ac.uk.

macro_5_0.png

Key People

The MACRO Trial is jointly led by Professor Claire Hopkins and Professor Carl Philpott, along with a multi-disciplininary team of researchers form University College London (UCL), University of Southampton and the Oxford Surgical Intervention Trials Unit (SITU).

If you would like to contact the clinical trial office, please email macrotrial@nds.ox.ac.uk

FUNDER & SPONSOR

The MACRO Trial is funded by the NIHR Programme Grants for Applied Research (ref RP-PG-0614-20011).

The MACRO Programme is sponsored by University College London (UCL).

USEFUL LINKS

What is a clinical trial
For more information on what a clinical trial is and why it's so important to undertake them, please visit the NHS Choices website

Information for Participants
For further information regarding the MACRO Trial, please visit the Information for Participants page.

Recruiting Centres 
To see which hospitals will be recruiting patients for the MACRO trial visit the Recruiting Centres page.

Recruitment Progress:

600
514

Date of latest recruit:

12 October, 2023

Site of latest recruit:

MACRO - Leeds Teaching Hospitals
  • MACRO logos

MACRO Trial Office
Surgical Interventions Trials Unit (SITU)
University of Oxford
Botnar Research Centre
Nuffield Orthopaedic Centre
Old Road, Headington
Oxford OX3 7LD

CONTACT
Email: macrotrial@nds.ox.ac.uk

The MACRO Programme
evidENT
UCL Ear Institute
90 Tottenham Court Road
Fitzrovia
London
W1T 4TJ

CONTACT
Phone: 020 3108 9326